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In D2 & D4, one study was classified as igh
References Garvey WT, Mechanick JI, Brett EM, Garber AJ, Hurley DL, Jastreboff AM, et al
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Gastrointestinal side effects are most common during dose escalation and may improve with slower titration or temporary interruption of treatment
"Cyclophosphamide versus methylprednisolone for treating neuropsychiatric involvement in systemic lupus erythematosus"
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